In a recent study published in The American Journal of Clinical Nutrition, researchers at the University of Cambridge assessed pre-fortification United Kingdom (UK) folate trends (2008-2019), especially in females of reproductive age, using National Diet and Nutrition Survey data. Study: National Diet and Nutrition Survey data reveal a decline in folate status in the UK … Read more
In a recent article published in Cell Death & Disease, researchers investigated the involvement of gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation in the context of inflammatory bowel disease (IBD). Specifically, they examined the effects of four phenolic acids, chlorogenic acid (CGA), ferulic acid (FA), caffeic acid (CA), … Read more
High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer’s early stages, when it’s easiest to treat. For patients with a pelvic mass (an abnormal lump or growth … Read more
As of 2020, approximately 5.8 million Americans suffer from Alzheimer’s disease, but recent groundbreaking research may provide hope to better understand and potentially prevent this devastating condition. The study led by researchers at New York Medical College (NYMC) and Eastern Virginia Medical School and published in Nature Communications Biology has unveiled a crucial link between … Read more
A recent Cell Death Discovery study discusses the role of Lactobacillus in treating inflammatory bowel disease (IBD). Study: The role of Lactobacillus in inflammatory bowel disease: From actualities to prospects. Image Credit: ART-ur / Shutterstock.com What is IBD? IBD involves chronic inflammation of the intestine that causes diarrhea, abdominal pain, and bloody stools. IBD comprises Crohn’s disease (CD) and ulcerative … Read more
In a recent review published in the Cell Death Discovery Journal, researchers explored the association between ferroptosis and male reproductive failure, emphasizing the need for tailored therapies and preventative efforts. Study: Emerging roles of ferroptosis in male reproductive diseases. Image Credit: Vladimir Sukhachev/Shutterstock.com Background Infertility is a rising concern globally, warranting research to identify novel targets that … Read more
New research has uncovered elevated rates of high blood sugar, or hyperglycemia, among patients with breast cancer who are treated with the oral medication alpelisib. The results are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Alpelisib targets the phosphoinositide 3-kinase (PI3K) protein that is involved in cell growth and when … Read more
A groundbreaking anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the Department of Chemistry at UNIST. This pioneering research promises a new paradigm for chemical anticancer drugs in the future. Lysosomes are crucial organelles responsible for breaking down … Read more
In a recent review published in Foods, a group of authors assessed the influence of Brazilian native fruits and their by-products on human intestinal microbiota and their potential role in mitigating non-communicable chronic diseases (NCDs) based on current scientific literature. Study: Evidence for the Beneficial Effects of Brazilian Native Fruits and Their By-Products on Human Intestinal … Read more
An international study has revealed strong associations between oral health and survival among people diagnosed with head and neck cancer. Specifically, better oral health, as evidenced by the number of natural teeth and dental visits prior to the time of diagnosis, was associated with increased survival. Importantly, those who had more frequent dental visits were … Read more