New MECP2 gene variant identified and characterized in Rett syndrome

New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic ‘hand-wringing’ movements, seizures, and cognitive disability. This incurable condition results from mutations in the methyl-CpG binding protein 2 (MECP2) gene that impairs the role of the MeCP2 protein in … Read more

New blood test could detect ovarian cancer early, improve treatment

New blood test could detect ovarian cancer early, improve treatment

High-grade serous ovarian carcinoma (HGSOC) is the most common type of ovarian cancer. It is also the most lethal form, in part because clinicians do not have effective ways to screen women for it during the cancer’s early stages, when it’s easiest to treat. For patients with a pelvic mass (an abnormal lump or growth … Read more

Promising new cervical cancer test fills in the gap missed by Pap tests

Promising new cervical cancer test fills in the gap missed by Pap tests

In a recent study published in the Journal of the National Cancer Institute, researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening. Study: A novel human papillomavirus and host DNA methylation score and detection of cervical adenocarcinoma. Image Credit: mi_viri/Shutterstock.com HPV … Read more