New insights into how our cells stay healthy

New insights into how our cells stay healthy

If we don’t take out the trash regularly, our homes become unpleasant and even a danger to our health. The same applies to our cells: If excess proteins and strands of genetic material aren’t removed, the cell and ultimately the entire organism can fall ill. For instance, scientists suspect there is a connection between Alzheimer’s … Read more

New TB treatments tackle the disease without wrecking your microbiome

New TB treatments tackle the disease without wrecking your microbiome

In a recent study published in the journal The Lancet Microbe, researchers examined the impact of six experimental treatment regimens and the standard-of-case treatment for tuberculosis on the respiratory microbiome obtained from sputum samples. Study: In a recent study published in the journal The Lancet Microbe, researchers examined the impact of six experimental treatment regimens … Read more

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen today announced data from the final analysis of the Phase 2 OCEAN(a)-DOSE study of olpasiran, a small interfering RNA (siRNA) during the Late-Breaking Science Session at the European Society of Cardiology (ESC) Annual Meeting being held in Amsterdam. In the off-treatment extension period, olpasiran showed a lasting effect on Lp(a) reduction nearly a year after the last dose. … Read more

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

Metagenomic next-generation sequencing as an emerging modality for the diagnosis of infectious diseases

A recent study published in the Open Forum Infectious Diseases Journal examined the role of plasma metagenomic next-generation sequencing (mNGS), a promising method for detecting infectious illnesses. Study: Impact of metagenomic next-generation sequencing of plasma cell-free DNA testing in the management of patients with suspected infectious diseases. Image Credit: ArtemisDiana/Shutterstock.com Background The ability to rapidly identify human … Read more