Early metformin therapy falls short in curbing gestational diabetes woes

Early metformin therapy falls short in curbing gestational diabetes woes

In a recent study published in the journal JAMA Network, researchers conducted a randomized clinical trial to investigate whether early metformin therapy can reduce insulin dependence and improve glycemic control in pregnant women who present symptoms of gestational diabetes. Their findings did not find outcome improvements in diabetes symptoms, contrasting previous scientific and medical beliefs. … Read more

Research provides new hope for expectant mothers suffering from gestational diabetes

Research provides new hope for expectant mothers suffering from gestational diabetes

Researchers at University of Galway have taken a significant step forward in the management of gestational diabetes mellitus after a clinical trial involving pregnant women provided new hope for expectant mothers suffering the condition. The findings from the trial are being published in JAMA: the Journal of American Medical Association. Gestational diabetes is a global … Read more

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

Mobile AI rivals specialists in diagnosing skin cancer, outperforms junior doctors

A recent Lancet Digital Health study assesses whether mobile phone-powered artificial intelligence (AI) could support the diagnosis and management of pigmented skin cancer. Study: Comparison of humans versus mobile phone-powered artificial intelligence for the diagnosis and management of pigmented skin cancer in secondary care: a multicentre, prospective, diagnostic, clinical trial. Image Credit: Gordana Sermek / Shutterstock.com Background Advanced machine learning … Read more

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

Kombucha tea shows promise in lowering blood sugar levels for type 2 diabetics

In a recent study published in Frontiers in Nutrition, researchers discuss the results of a  randomized controlled pilot clinical trial conducted at the Georgetown University Hospital investigating whether kombucha tea can reduce blood glucose levels in diabetic patients. Study: Kombucha tea as an anti-hyperglycemic agent in humans with diabetes – a randomized controlled pilot investigation. Image … Read more

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

Breast cancer patients treated with alpelisib have elevated rates of high blood sugar

New research has uncovered elevated rates of high blood sugar, or hyperglycemia, among patients with breast cancer who are treated with the oral medication alpelisib. The results are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society. Alpelisib targets the phosphoinositide 3-kinase (PI3K) protein that is involved in cell growth and when … Read more

Effective treatment for lower urinary tract symptoms linked to lower mortality risk in older men

Effective treatment for lower urinary tract symptoms linked to lower mortality risk in older men

Effective treatment for lower urinary tract symptoms (LUTS) in men aged 50 or older is associated with a lower risk of death over the next few years reports a study in the October issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott … Read more

Home-based oxygen therapy shows promise for improving wound healing after breast reduction surgery

Home-based oxygen therapy shows promise for improving wound healing after breast reduction surgery

In the last few years, breast reduction procedures in the U.S. have become increasingly common. According to the American Society of Plastic Surgeons, nearly 100,000 breast reduction procedures were performed in 2020. This procedure involves a high-tension T-Junction suture in which three incisions meet, forming the shape of a T. Larger breast reductions with longer … Read more

Illustrating the safety of a new drug treatment designed for spinal cord injury

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has demonstrated the safety and tolerability of a new drug treatment designed as a therapeutic intervention for spinal cord injury (SCI). The research, … Read more

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial. There are currently few effective treatment options for patients with recurrent ovarian cancer and other solid tumors, but City of Hope researchers are trying to change that. … Read more

What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

In a recent article published in Jama Network Open, researchers performed a secondary analysis of the ActiveBrains randomized clinical trial (RCT) in Granada, Spain, between November 1, 2014, and June 30, 2016, with two primary goals.  Study: Effects of an Exercise Program on Cardiometabolic and Mental Health in Children With Overweight or Obesity A Secondary Analysis … Read more