Neurology

Can ketogenic diet offer an effective alternative to antiseizure medication in infants with drug-resistant epilepsy?

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Can ketogenic diet offer an effective alternative to antiseizure medication in infants with drug-resistant epilepsy?

In a recent study published in The Lancet Neurology, researchers evaluated the effectiveness of ketogenic diets compared to anti-seizure medications in lowering seizure frequency among newborns with drug-resistant epilepsy. Study: Classic ketogenic diet versus further antiseizure medicine in infants with drug-resistant epilepsy (KIWE): a UK, multicentre, open-label, randomised clinical trial. Image Credit: SewCreamStudio/Shutterstock.com Background Epilepsy is commonly … Read more

Redefining the battle against Alzheimer’s with tau-focused treatments

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Redefining the battle against Alzheimer’s with tau-focused treatments

In a recent article published in the journal Nature Reviews Neurology, researchers discuss the efficacy of tau-targeting Alzheimer’s disease (AD) therapies and strategies that can be implemented to improve these treatments, especially immunotherapies. Study: Tau-targeting therapies for Alzheimer disease: Current status and future directions. Image Credit: Gorodenkoff / Shutterstock.com Background Since 2018, the prevalence of AD has increased … Read more

Groundbreaking research may provide hope to better understand and prevent Alzheimer’s disease

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Groundbreaking research may provide hope to better understand and prevent Alzheimer’s disease

As of 2020, approximately 5.8 million Americans suffer from Alzheimer’s disease, but recent groundbreaking research may provide hope to better understand and potentially prevent this devastating condition. The study led by researchers at New York Medical College (NYMC) and Eastern Virginia Medical School and published in Nature Communications Biology has unveiled a crucial link between … Read more

More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

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More pregnancies and longer reproductive lifespan may protect against cerebral small vessel disease

People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study published in the September 27, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. Cerebral small vessel disease, a form of cerebrovascular disease, results from … Read more

Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

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Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine. These evidence-based, consensus guidelines provide clinicians with a framework for the … Read more

A pilot cohort study on infants with new-onset epilepsy examines the clinical utility of rapid genome sequencing

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A pilot cohort study on infants with new-onset epilepsy examines the clinical utility of rapid genome sequencing

In a recent study published in the Lancet Neurology, researchers evaluated the clinical impact of rapid genome sequencing of infants with new-onset epilepsy using their biological parents as probands.  To this end, they performed a multicentre pilot cohort study of the International Precision Child Health Partnership (IPCHiP), a consortium of four pediatric centers providing tertiary pediatric … Read more

AI-powered eye scans could revolutionize early detection of Parkinson’s

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AI-powered eye scans could revolutionize early detection of Parkinson’s

Markers that indicate the presence of Parkinson’s disease in patients on average seven years before clinical presentation have been identified by a UCL and Moorfields Eye Hospital research team. This is the first time anyone has shown these findings several years before diagnosis, and these results were made possible by the largest study to date … Read more

Machine learning can accurately predict subtypes of Parkinson’s disease

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Machine learning can accurately predict subtypes of Parkinson’s disease

Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson’s disease using images of patient-derived stem cells. Their work, published today in Nature Machine Intelligence, has shown that computer models can accurately classify four subtypes … Read more