A common concern about gender-affirming hormone therapy for transmasculine people is the risk of red blood cell volume changes and erythrocytosis, a high concentration of red blood cells, with the use of prescribed testosterone. However, Mount Sinai researchers have found that testosterone treatment may be safer than previously reported, with results published today in The … Read more
A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development … Read more
Menopause, or climacteric, is a change that occurs and profoundly impacts the lives of half the world’s population at some point. Best practices in the clinical management of this transition have been published earlier, in 2014, as the The Practitioner’s Toolkit for Managing the Menopause. The revised Toolkit has now been released, incorporating newer published … Read more
In vitro fertilization (IVF) is a time-intensive and often stress-inducing fertility procedure. Yet how does that stress impact its success? Investigators at Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, assessed the effects of anxiety and depression in men on fertility and IVF outcomes. Their findings reveal no correlation … Read more
Survival rates for men with metastatic prostate cancer have increased by an average of six months, something which coincides with the gradual introduction of ‘dual treatment’ since 2016. This is according to a register study of all Swedish men diagnosed between 2008 and 2020. The results are published in the medical journal JAMA Network Open. … Read more
Most contraceptive pills are based on a cycle of taking the pill for 21 days, and then stopping the pill for 7 days. Now researchers have found that women’s mood worsens during the 7 pill-free days. This work will be presented at the ECNP congress in Barcelona on 8th October, after recent publication (see notes). … Read more
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of cerebral small vessel disease, according to a new study published in the September 27, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. Cerebral small vessel disease, a form of cerebrovascular disease, results from … Read more
New research from Queen Mary University of London, published in iScience, shows an increased risk of blood clots in women who have any combination of a particular gene mutation, estrogen use, or common medical conditions – specifically: obesity, high blood pressure, high cholesterol, and kidney disease. Women with the Factor V Leiden (FVL) gene mutation … Read more
In a review article published in the journal Cell, renowned experts have provided a detailed overview of menopause biology, clinical outcomes, therapeutic options, and supportive care. “The road to menopause is not difficult for all, but for some, symptoms may be severe or even disabling and disruptive to work and family,” write the authors, who … Read more
New research, from men’s healthcare company Numan, suggests there is a sleep crisis among UK men with 71% of men surveyed struggling to sleep through the night. The survey reveals that men are not sleeping for long enough and that, when they do fall asleep, the quality of their rest is low. The findings are … Read more