A promising match or a questionable pair?

A promising match or a questionable pair?

In a recent review published in the journal Diabetes Therapy, researchers weighed the evidence regarding ketogenic diets and their efficacy for the treatment of type 1 diabetes (T1D), type 2 diabetes (T2D), and gestational diabetes (GD). Their findings indicate that many questions on this subject remain unresolved and that many further investigations are needed before … Read more

Breakthrough treatments face manufacturing and efficacy

Breakthrough treatments face manufacturing and efficacy

In a recent review published in Gene Therapy, a group of authors explored the progress and persistent hurdles in gene therapy for inherited blood disorders, malignancies via chimeric antigen receptors (CAR)-T cells, and varied diseases treated with in vivo adeno-associated virus (AAV) vectors, addressing the transformative cures and the economic and manufacturing complexities involved. Study: … Read more

The 2023 toolkit for healthcare practitioners

The 2023 toolkit for healthcare practitioners

Menopause, or climacteric, is a change that occurs and profoundly impacts the lives of half the world’s population at some point. Best practices in the clinical management of this transition have been published earlier, in 2014, as the The Practitioner’s Toolkit for Managing the Menopause. The revised Toolkit has now been released, incorporating newer published … Read more

Experts call for individualized treatment and more research

Experts call for individualized treatment and more research

In a review article published in the journal Cell, renowned experts have provided a detailed overview of menopause biology, clinical outcomes, therapeutic options, and supportive care. “The road to menopause is not difficult for all, but for some, symptoms may be severe or even disabling and disruptive to work and family,” write the authors, who … Read more

New consensus statement provides guidance for use of 177Lu-PSMA radionuclide therapy in mCRPC patients

New consensus statement provides guidance for use of 177Lu-PSMA radionuclide therapy in mCRPC patients

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has issued a new consensus statement to provide standardized guidance for the selection and management of metastatic castrate-resistant prostate cancer (mCRPC) patients being treated with 177Lu-PSMA radionuclide therapy. The statement, published in the July issue of The Journal of Nuclear Medicine, also reviews current clinical struggles … Read more

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

Mediterranean diet with a dairy twist shows promise in lowering heart disease risk

A recent Nutrients journal study evaluated how the combination of Mediterranean diet (MedDiet) supplement and dairy foods affected the gut microbiome in Australians at a high risk of cardiovascular disease (CVD). Study: Interactions between Mediterranean Diet Supplemented with Dairy Foods and the Gut Microbiota Influence Cardiovascular Health in an Australian Population. Image Credit: DiViArt / Shutterstock Background Diet plays … Read more

Ketogenic diets, gut microbiota, and health effects

Ketogenic diets, gut microbiota, and health effects

In a recent study published in the Nutrients Journal, researchers summarized the evidence on ketogenic diets (KDs) from the past three decades. ​​​​​​​Study: The Influence of Ketogenic Diet on Gut Microbiota: Potential Benefits, Risks and Indications. Image Credit: Boontoom Sae-Kor/Shutterstock.com Background KD is characterized by minimal intake of carbohydrates, low calories, standard protein levels, and high fat … Read more

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

MGH opens first-of-its-kind center to eliminate lifelong immunosuppression after organ transplant

Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham health system, officially opened the Legorreta Center for Clinical Transplant Tolerance, the first-of-its kind center in the world dedicated to preventing organ rejection after transplant surgery without the use of lifelong immunosuppressive medications. Immunosuppressive medications prevent the immune system from rejecting a transplanted … Read more