Inflammasome

Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

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Might a polyphenol-rich dietary approach hold the answers for managing inflammatory bowel disease?

In a recent article published in Cell Death & Disease, researchers investigated the involvement of gut microbiota and macrophage-neutrophil interactions in the impact of dietary phenolic acids on intestinal inflammation in the context of inflammatory bowel disease (IBD).  Specifically, they examined the effects of four phenolic acids, chlorogenic acid (CGA), ferulic acid (FA), caffeic acid (CA), … Read more

A metabolic makeover boosting immunity and battling inflammation

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A metabolic makeover boosting immunity and battling inflammation

Western dietary (WD) habits are known to cause many of today’s non-communicable diseases by promoting chronic inflammation. Recently, to counteract WD-induced metaflammation, ketogenic diets (KD) have emerged. Given the drastic change in nutrient composition during KD, it is reasonable to hypothesize large-scale changes in the human metabolome. Furthermore, this alteration in the metabolome could also … Read more