Breakthrough treatments face manufacturing and efficacy

Breakthrough treatments face manufacturing and efficacy

In a recent review published in Gene Therapy, a group of authors explored the progress and persistent hurdles in gene therapy for inherited blood disorders, malignancies via chimeric antigen receptors (CAR)-T cells, and varied diseases treated with in vivo adeno-associated virus (AAV) vectors, addressing the transformative cures and the economic and manufacturing complexities involved. Study: … Read more

A metabolic makeover boosting immunity and battling inflammation

A metabolic makeover boosting immunity and battling inflammation

Western dietary (WD) habits are known to cause many of today’s non-communicable diseases by promoting chronic inflammation. Recently, to counteract WD-induced metaflammation, ketogenic diets (KD) have emerged. Given the drastic change in nutrient composition during KD, it is reasonable to hypothesize large-scale changes in the human metabolome. Furthermore, this alteration in the metabolome could also … Read more