Cell

Statins may reduce breast cancer mortality rates

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Statins may reduce breast cancer mortality rates

In a recent study published in JAMA Network Open, researchers determined the relationship between serological cholesterol levels, statin usage, and breast cancer (BC) mortality. Study: Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer. Image Credit: artemevdokimov/Shutterstock.com Background Breast cancer is the most prevalent cancer in women across the world, with satisfactory survival rates but … Read more

AI tools show promise in personalized cancer treatment, but lag behind human experts

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AI tools show promise in personalized cancer treatment, but lag behind human experts

Treating cancer is becoming increasingly complex, but also offers more and more possibilities. After all, the better a tumor’s biology and genetic features are understood, the more treatment approaches there are. To be able to offer patients personalized therapies tailored to their disease, laborious and time-consuming analysis and interpretation of various data is required. Researchers … Read more

Breakthrough treatments face manufacturing and efficacy

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Breakthrough treatments face manufacturing and efficacy

In a recent review published in Gene Therapy, a group of authors explored the progress and persistent hurdles in gene therapy for inherited blood disorders, malignancies via chimeric antigen receptors (CAR)-T cells, and varied diseases treated with in vivo adeno-associated virus (AAV) vectors, addressing the transformative cures and the economic and manufacturing complexities involved. Study: … Read more

Andrew Buchanan’s Impact on Biologics Innovation

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Andrew Buchanan’s Impact on Biologics Innovation

Following ELRIGs Drug Discovery Conference, News Medical took part in an insightful discussion with Dr. Andrew Buchanan, a renowned figure in the realm of biopharmaceutical research. Dr. Buchanan’s career spans 22 years, notably at Cambridge Antibody Technology, MedImmune, and AstraZeneca, where he has significantly contributed to the development of 18 antibody-based drugs, including three successful … Read more

Children need to be screened for vision problems as often as adults with sickle cell disease, study suggests

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Children need to be screened for vision problems as often as adults with sickle cell disease, study suggests

Sickle cell disease is a rare, inherited disorder in which the red blood cells become hard, sticky, and change shape, resembling the farm tool. People who have it can sometimes develop vision problems when these sickle-shaped cells get trapped in the small blood vessels as the back of the eye. Sickle retinopathy is an age-dependent … Read more

Study sheds light on origins of breast cancer in people with BRCA2 mutations

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Study sheds light on origins of breast cancer in people with BRCA2 mutations

A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development … Read more

New MECP2 gene variant identified and characterized in Rett syndrome

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New MECP2 gene variant identified and characterized in Rett syndrome

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic ‘hand-wringing’ movements, seizures, and cognitive disability. This incurable condition results from mutations in the methyl-CpG binding protein 2 (MECP2) gene that impairs the role of the MeCP2 protein in … Read more

Plant-based materials will be the building blocks for soft medical microrobots

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Plant-based materials will be the building blocks for soft medical microrobots

A team of University of Waterloo researchers has created smart, advanced materials that will be the building blocks for a future generation of soft medical microrobots.  These tiny robots have the potential to conduct medical procedures, such as biopsy, and cell and tissue transport, in a minimally invasive fashion. They can move through confined and … Read more

Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

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Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

Today, the Chan Zuckerberg Initiative (CZI) announced the launch of a new biomedical research hub in New York City that will catalyze collaboration between leading scientific and technology institutions in the area, with the goal of solving grand scientific challenges on 10- to 15-year time horizons. The Chan Zuckerberg Biohub New York (CZ Biohub NY) … Read more

Impact of ketogenic diets on breast cancer

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Impact of ketogenic diets on breast cancer

In a recent review published in Nutrients, researchers explored the therapeutic potential of the ketogenic diet (KD) for breast cancer (BC). Study: Ketogenic Diet and Breast Cancer: Recent Findings and Therapeutic Approaches. Image Credit: Boontoom Sae-Kor/Shutterstock.com Background BC, the most common cancer in women, is greatly influenced by dietary patterns. The ketogenic diet (KD), characterized by a … Read more